As previously described, the glomerulus consists of the nephron capsule (Bowman’s capsule) and the ingoing capillary network. and is where the blood is filtered. The driving force behind the filtration is the blood pressure (creating a hydrostatic pressure) in the capillaries, and the capillaries and the wall of Bowman’s capsule is perforated and structured in such a manner that water and small molecules easily pass through. Larger molecules and molecules with a negative charge (which is mainly medium-sizedand large proteins) will not pass through the perforations in the capillaries and into Bowman’s capsule. The filtrate therefore should not contain large molecules like proteins.